Introduction of stop codon and consistent inheritance of the mutation with the disorder indicated its pathogenic nature. |
The researchers changed the anticodon in their new tRNA to match up with the UAG stop codon instead of the codon for glutamine. |
Gentamicin is an antibiotic that causes the RNA translation mechanism in the ribosomes to ignore such a premature stop codon, i.e. to read through it. |
Evidence against either a premature stop codon or the absence of Ob gene mRNA in human obesity. |
We report 3 cases with 1 homozygous and 2 heterozygous mutations at codon 37 causing a premature stop codon. |
Their dystrophin gene has a point mutation in the splice receptor site of intron 6 which leads to the deletion of exon 7 in the mRNA, to a frame shift, and a premature stop codon. |