| The most widely known pyrogen is the endotoxin lipopolysaccharide, which is produced by gram-negative bacteria. |
| Sheaths that contact brain tissue must be pyrogen free. |
| This will encourage successful transfer of the tests and help open new fields for pyrogen testing, such as cellular therapies, medical devices and pollution control in the work place. |
| The pyrogen test is a safety test for the detection of contaminants in medical products. |
| The rabbit pyrogen test is well established as an official end-product test. |
| Six alternative cellular assays have therefore been developed to replace the animal rabbit pyrogen test and close the safety gap presented by use of the LAL test in controlling parenterals. |
