| Acinar cells surrounding the necrotic foci showed atrophy and necrobiotic changes, and numerous eosinophilic intranuclear inclusions with clear halos were noted. |
| Histopathologic examination of the tissue showed a necrobiotic granuloma with associated histiocytic infiltration. |
| Due to the absence of hyaline necrobiosis, a diagnosis of necrobiotic xanthogranuloma was therefore made. |
| Granuloma annulare, which is characterized by necrobiotic dermal papules, is a benign inflammatory dermatosis of unknown cause. |
| Histologic analysis demonstrated a palisading, necrobiotic granulomatous dermatitis with increased interstitial mucin consistent with granuloma annulare. |
| The complicated changes taking place during metamorphosis, especially in the case of necrobiotic metamorphosis, must be performed in a coordinated way. |
