Due to its similarity to LH, urine-derived hCG has been used to trigger ovulation and luteinization and to support the corpus luteum. |
However, this complex process initiated by ovulation and followed by luteinization, similar to wound healing or tumor formation, needs to be highly regulated and coordinated. |
Premature luteinization in controlled ovarian hyperstimulation has no adverse effect on oocyte and embryo quality. |