| An area of local edema becomes a pruritic macule or papule, which enlarges and ulcerates after one to two days. |
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| In the classic form, it evolves from a macule to a papule and finally to an erosion or ulcer. |
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| The lesion on the abdomen began as an asymptomatic small light red macule following scratch. |
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| This rash usually begins as an erythematous macule or papule that rapidly expands centrifugally, often with central clearing. |
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| The hair cells of the utricle and sacule are concentrated in an area called the macule. |
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| Sometimes it presents as a white scale over a pink macule or papule. |
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| The centre of the macule may fade to generate pink rings that can be mistaken for ringworm. |
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| Barilli noted a 5 millimeter variegated macule with irregular borders on Susan's right deltoid and a 1 centimeter brown hazy macule with surrounding erythema. |
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| Clinical features of regression include flattening of lesions, reduction in lesion size, and change from a purple-red appearance to an orange-brown macule. |
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