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What is another word for irreversibly?

Need synonyms for irreversibly? Here's a list of similar words from our thesaurus that you can use instead.

Without any chance of redemption or saving
“Ozone is a toxic gas, that in large quantities, can cause irreversible damage to lung tissue and the respiratory tract.”
In a manner that is fixed and never changing
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“The Presiding Officer does not at this time desire to make any binding or irreversible rule.”
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